They occur in middle-aged or older dogs. Two forms of histiocytosis affect Bernese Mountain Dogs. Affected dogs have multiple collagenous nevi that are associated with kidney and uterine tumors. In dogs, they can occur at any age but are found most commonly during late middle age. Wide surgical removal is the treatment of choice for angiosarcomas below the skin surface. Use to remove results with certain terms These tumors generally appear as firm, solitary, dome-shaped elevated masses, which are often hairless or ulcerated. Skin tumors are diagnosed more frequently than other tumors in animals in part because they are the most easily seen tumors and in part because the skin is constantly exposed to many tumor-causing factors in the environment. These tumors are most common on the legs and trunk. If the entire tumor cannot be removed, reducing the size of the tumor can help improve signs. These changes may also appear in the mouth or on the lips, eyelids, or footpads. Although generally solitary, melanomas may be multiple, especially in the breeds at risk. They are firm and often feel like a . These may appear anywhere on the body and may involve other parts of body like the lymphatic system, respiratory system and frequently the renal system (kidneys). Newest results Two surgeons, a man and a woman, perform surgery to remove. Chronic trauma, especially at pressure points (e.g., the elbows), can cause changes in the way the skin rebuilds itself leading to these benign tumors. Peripheral Odontogenic Fibroma (POF) These are the most common odontogenic tumors diagnosed in dogs. Systemic histiocytosis of Bernese Mountain dogs is an aggressive skin disease that causes multiple skin lesions that wax and wane. These slow-growing fibrous tissue growths are most common on older dogs and often appear on the dewlap (the loose, wrinkly skin around the neck), eyelids, ears and under the armpits. [3] It is usually painless. For malignant adenocarcinomas, surgery is the treatment of choice. Lipomas generally occur in older, obese females, most commonly on the trunk and near the tops of the legs. They can also. E. Traumatized fibroepithelial polyp. Masses may also develop in internal organs, such as the lymph nodes, spleen, and bone marrow. The outlook is guarded. Some are caused by prolonged sun exposure. Most warts appear as bumps with a hardened surface resembling a cauliflower. These are elongated or circular, roughly 2 inches (5 centimeters) in length or diameter. They can occur in dogs of any age, however. Blood-filled skin tag. For information on viral warts, see below. For these reasons, epidermal hamartomas are usually removed or treated. For diffuse or multiple forms, surgical removal or freezing have been less successful. Malignant melanomas grow quickly and have great potential to spread to other organs. Tumors are usually small lumps or bumps, but they also can occur as hairless, discolored patches, rashes, or nonhealing ulcers. Adenocarcinoma is the most common malignant rectal tumor. Fibrosarcomas are slow-growing, malignant (cancerous) tumors most often found in the connective tissue of the skin and beneath the skin. "Narrow" margins describe tumor cells close tobut not atthe edge, indicating that tumor cells could possibly be left behind at the surgical site. The most visible symptom of a lipoma is the formation of lumps or fatty tumors on dogs, which you can easily feel with your bare hands. They rarely spread to other sites. Treatment for the multiple form is more difficult, because the tumors are more likely to return following surgery. Surgical removal is the treatment of choice. In many cases, nonepitheliotropic skin lymphosarcoma is, by appearance, indistinguishable from epitheliotropic skin lymphosarcoma. Most are recognized in older male dogs in which they usually develop on the chest and legs. When present on the lips or in the mouth, the tumors appear as dark to light gray or pink raised lumps. Already have a myVCA account? Your dogs body will react to the cyst contents as a foreign substance, which can cause severe inflammation. The trusted provider of veterinary information since 1955, Dermatitis and Dermatologic Problems in Dogs, Congenital and Inherited Skin Disorders in Dogs, Abscesses Between the Toes (Interdigital Furunculosis) in Dogs, Hyperpigmentation (Acanthosis Nigricans) in Dogs, Mite Infestation (Mange, Acariasis, Scabies) in Dogs, Whole-body Disorders that Affect the Skin in Dogs, Last review/revision Jun 2018 | Modified Oct 2022. Treatment is surgery to remove the tumor. Sebaceous gland adenomas are common in older dogs. They can be found in all domestic animals. Thousands of new, high-quality pictures added every day. These are benign tumors that come from the skin and subcutaneous connective tissue cells known as fibroblasts. When removing these cancerous cells, the veterinarian will usually remove not only the visible tumor but also a wide margin of tissue surrounding it. Unknown and chronically debated histogenesis and naming of this tumor; the name will likely be changed again in the future. They are benign, but their appearance is unpleasant, and they are prone to secondary bacterial infection. The head and extremities are the most likely sites. Surgery to remove these tumors is the treatment of choice. They can be either benign or malignant. Peripheral Odontogenic Fibroma. Chemotherapy may also be recommended. o [alopecia OR hair loss ], , DVM, Pawspice & Animal Oncology Consultation Service. Fibromatosis is a thickening and invasive growth in tendon sheaths. Small lymphoid lumps are scattered throughout the tissues. They may spread to other organs, including lymph nodes and the lungs. The nomenclature is varied throughout the veterinary literature, but these tumours are most correctly known as peripheral odontogenic fibromas. The term "fibroblastic" or "fibromatous" is used to describe tumors of the fibrous connective tissue. The overlying skin dimples on pinching the lesion - the dimple or pinch sign. They may develop anywhere on the body surface as well as in internal organs, but the limbs (especially the back of the upper thigh), lower abdomen, and chest are the most common sites. Complete surgical removal is the treatment of choice. They are often called spindle-cell sarcomas. They often invade underlying muscles. Nasopharyngeal angiofibroma is a well-described disease in humans. A dermatofibroma is tethered to the skin surface and mobile over subcutaneous tissue. Tumors can develop anywhere on the body but most commonly on the trunk in dogs. Fibromatoses are generally indistinguishable from infiltrative fibrosarcomas (see below) except by microscopic examination. If your pet has developed these tumors over the elbows (at pressure points), your pet may benefit from a bed to alleviate elbow discomfort. Peripheral odontogenic fibroma (formerly known as fibromatous and ossifying epulis) is a benign, often slow-growing tumor that arises from periodontal structures. Sometimes they can grow outward with a surface like a wart. They can be benign or malignant. Overview of Tumors of the Skin and Soft Tissues in Animals, Soft Tissue Giant Cell Tumors (Fibrous Histiocytomas), Tumors Originating Outside the Skin (Metastatic Tumors). If feasible, surgical removal is the treatment of choice. Thus, all mast cell tumors are normally treated as at least potential malignancies. Fibromas are benign tumors that originate from skin and subcutaneous connective tissue cells called fibroblasts. Apocrine adenomas appear as firm to soft cysts, seldom larger than 1.6 inches (4 centimeters) in diameter. Diagnosis Edge biopsy revealed squamous cell carcinoma. Cocker Spaniels, Airedales, Scottish Terriers, and Standard Poodles are most at risk. Therefore, during surgery the tumor itself and a wide margin of tissue around it will be removed. Bloodhounds, Basset Hounds, and Standard Poodles are at greatest risk. Exophytic gingival lesions represent some of the more frequently encountered lesions in the oral cavity. In some cases, this may mean amputation of a limb. Siberian Huskies, Alaskan Malamutes, and Bulldogs are most likely to develop this tumor. These tumors can develop anywhere on the body, but they occur most frequently on the back, tail, and legs. They are classified as osteoclastic giant cell-rich bone tumors 1,2. Rupturing Schnauzer bumps only aggravates the condition and increases the chance of infection. Apocrine ductular adenomas are less common than apocrine adenomas. Dogs with subungual squamous cell carcinomas first show lameness or malformation, infection, or loss of a claw. Fibromatosis can spread to nearby tissue but does not spread through the bloodstream to distant organs. In addition, chemotherapy and radiation treatment may also be provided. Chemotherapy for sarcomas has become a more common method of treatment. "Wide" or "clean" margins describe tumors cells far from the edge of the removed tissue, indicating it is unlikely that tumor cells remain at the surgical site. These tumors usually invade into surrounding tissues. However, dogs that develop one such tumor are prone to develop more at other sites. So, he's undergoing complex surgery to remove his fibroma . They are bumps with a dark dot in the center. Epidermal hamartomas (nevi) are dark, pointy bumps on the skin. Blood vessel (vascular) tumors of the skin and soft tissues are growths that closely resemble blood vessels. The skin tumors are recognized first, and kidney disease develops 3 to 5 years later. Generally, these are multiple tumors. Non-ossifying fibromas (NOF) are benign and generally self-limiting osteoclastic giant cell-rich bone tumors typically found in the metaphyses of long bones . Some dogs develop cysts that are filled with keratin, a skin protein. Bloat: First Aid. Surgical removal of the tumors may be used to remove extremely large or ulcerated tumors that have become secondarily infected. Older English Cocker Spaniels, Springer Spaniels, Dachshunds, Alaskan Malamutes, German Shepherds, and mixed-breed dogs are most at risk. "Early detection of oral tumors directly correlates with clinical prognosis for many tumor . Liposarcomas are rare tumors in all domestic animals. They are often smaller, firmer, and less cystic than apocrine adenomas. Pilomatricomas are hair follicle tumors that appear similar to trichoepitheliomas, but their cystic contents are often gritty. They are typically slow-growing and not bothersome to your pet. This form of histiocytosis does not typically affect any internal organs but can cause dogs to appear unsightly. Males are affected more often than females. A benign growth of these cells is a basal cell tumor. Radiation treatment is often added following the surgery. Fibrosarcomas vary greatly in appearance and size. They are malignant tumors with a low potential to spread to other sites. Diagnosis is by finding the cysts on the dog. In dogs 86 percent of vaginal tumors are benign smooth muscle tumors, often with fingerlike extensions (e.g., leiomyoma, a type of smooth muscle tumor; fibroleiomyoma, a fibrous tissue and smooth muscle tissue tumor; and fibroma, a fibrous tissue tumor). Blastomycosis is a Systemic Fungal infection Affecting Dogs and Cats. Most have a dark surface. These tumors appear as white, firm, lumps. The tumors are generally small (less than 2 inches [5 centimeters]) in diameter and sometimes narrow. Distinguishing a tumor from an inflammatory disease can sometimes be difficult. Chemotherapy can relieve signs but this form of cancer often recurs. Treatment is dependent on size . During the surgery, your veterinarian will remove tissue around the tumor to reduce the chances of it recurring. Fibromas are noncancerous lumps that form on irritated or injured gum tissue. Cutaneous fibromas are hairless tumors that can be found on any part of the skin but are more commonly confined to the face, eyes, neck and forelegs. Fibromas are mostly slow-growing and benign (non-cancerous). Merck & Co., Inc., Rahway, NJ, USA(known as MSD outside of the US and Canada) is dedicated to using the power of leading-edge science to save and improve lives around the world. Log in 24/7 to access your pets health care information. Siberian Huskies, Samoyeds, Pekingese, and Cocker Spaniels are the breeds most commonly affected. Those that have been reported have been malignant and found in dogs and cats. Mast cell tumors are tricky and difficult to deal with because they appear as a large central tumor but are in fact surrounded by a halo of smaller, microscopic nests of mast cells that infiltrate normal-looking skin. These tumors frequently spread to other organs and do so early in the course of the disease. Doberman Pinschers, Boxers, and Golden Retrievers are most at risk. Because of this, and because it is important to identify whether the tumor is cancerous, they should be removed. Use OR to account for alternate terms There are several tumors that arise from the connective tissue that provides a covering for nerves. If the margins are not clean and radiation treatment is not elected, chemotherapy is also an effective followup treatment. It is important to remove all of the tumor during the first surgery, because sarcomas that recur have a greater potential to invade local tissue, and they may also spread to other parts of the body. Some dogs grow new tumors periodically. The skin may appear rough, darkened and look like it has progressively degenerated (looks less healthy). Trichoepitheliomas are multiple small lumps in which an entire hair follicle is filled with condensed, yellow, granular, cheesy material. Tumors that grow rapidly or that are not removed completely during surgery are also more likely to spread. Other signs that it may be bothering your pup. Benign tumors are most common on the trunk of middle-aged dogs. POF was previously known as a type of epulis, with "epulis" being an outdated umbrella term for a gingival (gum) mass. "Dirty" margins describe tumor cells that extend to the edge of the removed tissue, indicating that tumor cells still remain in the dog's body. A rare variant of this tumor, diffuse lipomatosis, has been identified in Dachshunds, in which virtually the entire skin is affected, resulting in prominent folds in the skin on the neck and trunk. However, this disease may also be secondary to whole-body, internal diseases, such as canine malignant lymphoma Malignant Lymphoma in Dogs Malignant lymphoma is a common cancer in dogs. Norwegian Elkhounds, Belgian Sheepdogs, Lhasa Apsos, and Bearded Collies are most likely to develop these tumors. This tissue covers the. Signs vary widely and may include flaky skin, red patches on the skin surface, raised and ulcerated areas, or lumps deep within the skin. The veterinarian will remove a 2- to 3centimeter margin of tissue surrounding the sarcoma. The terms keloidal fibroma and keloidal fibrosarcoma can be applied to these lesions. Infrequently, viral warts in dogs may progress to invasive squamous cell carcinomas. I'm currently an RT student in my senior year. Amputation neuromas are disorganized growths that form after amputation or traumatic injury. The head and abdomen are affected most often. MEN 2B should be considered in a patient with bilateral flesh colored nodules in the commissures of the mouth or multiple . As a general rule, the tumors are solitary and are commonly found on the flanks, limbs, and groin. Basal cell carcinomas are less common in dogs than in cats. The tumors are lumps or plaques that often develop on the trunk. They appear as plaques, nodules, or small masses on or in the skin. Various treatments, including surgical removal, chemotherapy, and, less frequently, radiation treatment have been used both singly and in combination. This tumor most commonly occurs where the front legs meet the trunk and near the groin. The head and legs are the most likely sites. Your veterinarian will remove not only the tumor but also tissue around the tumor, including involved lymph nodes. Peripheral odontogenic fibroma (POF) is a tumor composed primarily of odontogenic mesenchyme. The breeds most at risk are Doberman Pinschers, Labrador Retrievers, Miniature Schnauzers, and mixed-breed dogs. Cysts may also form. They are usually treated by surgical removal. Affected dogs may be isolated from susceptible ones, but with the long incubation period (months), many are likely to have been exposed before the problem is recognized. Because it is hard to determine the tumors edges during surgery, recurrence is common (more than 70% return within 1 year of the initial surgery). Both forms of apocrine gland cysts are benign (not cancerous). a fibrosarcoma is made up of fibrous collagen material. 13 Ossifying fibroma is an expansile, lytic, and invasive mass that develops within the bone, particularly the mandible. They can invade surrounding tissues but rarely spread to other sites. Unlike basal cell tumors, basal cell carcinomas can be found almost anywhere on the body. Generally, it is difficult to identify the primary tumor based on the signs in the skin. Some soft tissue giant cell tumors are malignant (cancerous). There are both benign and malignant forms. They develop on the underside of dogs because the poorly haired skin offers minimal shielding from ultraviolet radiation. Most squamous cell carcinomas are solitary tumors. In some cases, a combination of radiation treatment, chemotherapy at the tumor location, and hyperthermia of the site (carefully increasing the body temperature of the affected area while under anesthesia) may be more effective than radiation alone. Many animals sun themselves lying on their backs. They may appear the same pinkish color as the gums, or can appear red and inflamed. However, they spread, forming new ulcers. In dogs, these are the most frequently diagnosed carcinomas of the skin. Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Nodular dermatofibrosis is rare in dogs but is most commonly seen in German Shepherds with tumors of the kidney or uterus in intact (unspayed) females. If the tumors are nodular or mass-like, a biopsy may be required to obtain an accurate diagnosis. If attached, it is known as an infiltrative dog lipoma. In most cases, surgery requires removal of the mass and tissues surrounding it, including involved lymph nodes. These tumors spread, especially to the lungs and liver. Tumors are abnormal growths of cells. [3] It typically results from mild trauma such as an insect bite. They can be further sub-classified as peripheral odontogenic fibromas and acanthomatus ameloblastomas. Apocrine gland cysts are found in middle-aged or older dogs. Malignant pilomatricomas are rare tumors of old dogs. These tumors are not well understood. Up to 95% of male dogs with these tumors are cured by castration. Tumors affecting the skin or the tissue just under the skin are the most commonly seen tumors in dogs. In dogs, they are found in older animals. The breeds prone to sun-caused angiosarcomas are Whippets, Italian Greyhounds, white Boxers, and Pit Bull Terriers. Although basal cell tumors are benign, they can be large and may cause extensive ulceration and secondary inflammation. The head, neck, and legs are the most frequent sites. Tumors arising under the skin surface may look lumpy. It is primarily a disease of middle-aged and older dogs, most often found in Poodles and Cocker Spaniels. The latter is done by microscopically evaluating the edge of the resected tissue (the "margins") to see whether tumor cells are present. In a lecture at the 2017 American Veterinary Medical Association Convention in Indianapolis, Indiana, Dr. Vicari said that oraltumors make up 6% of all tumors in dogs and discussed the need for clinicians to recognize and treat these tumors promptly. Neurofibromas and neurofibrosarcomas are other tumors that grow in the connective tissue around a nerve. A vaccine is available that helps shrink the size of malignant melanomas in dogs and may prolong survival. Diagnosis: Irritational fibroma. Symptoms and Types Excess salivation The head and legs are the most likely sites. o [pig guinea] If your pet has developed these tumors as a result of repeated self-trauma due to allergies or skin disease, they may not resolve without attempting to control the underlying problem. Irritation fibromas are the most common oral reactive lesion. Diagnosis is by finding the tumors on the animal and confirming the type of tumor with a fine needle aspiration or a biopsy. Fibromatous epulis is the name for a tumor that is usually located in the margin of the gums. Some involve hair follicles and glands, and these are called fibroadnexal hamartomas. However, the spreading nature of the tumor may make this difficult. Small mast cell tumors may remain quiet and seem inactive for long periods before spreading. Although uncommon, the disease can also affect other breeds. Cavalier King Charles Spaniels, Cocker Spaniels, and Scottish, Cairn, and West Highland White Terriers are the breeds most at risk. This may be the most prudent option, especially in aged dogs. Pieces of the tumor are then examined by a veterinary pathologist under the microscope. The second kind of wart in dogs is skin warts, which are indistinguishable from the warts that develop on or around mucous membranes. For this reason, you should avoid brushing the sore. Fibrosarcoma is the soft tissue cancer of dogs commonly found in the skin, long bones, trunk, neck, mouth, and jaws. Dogs that develop a sebaceous gland overgrowth or adenoma often develop new tumors at other sites. Few dogs survive longer than 6 months after diagnosis. Hemangiomas are single to multiple, circular, often compressible, red to black lumps and can look like a blood blister. Although they are benign, they tend to develop ulcers and some grow quite large. Dermatofibroma size varies from 0.5-1.5 cm diameter; most lesions are 7-10 mm diameter. The Merck Veterinary Manual was first published in 1955 as a service to the community. Surgical removal is the treatment usually recommended. Many treatments for skin lymphosarcoma have been tried, though no treatment has been shown to be completely successful. Surgical removal is the cure. 1,2 There is some evidence of similar features between nasopharyngeal angiofibroma in humans and dogs, 5 but data regarding this disease in dogs is limited. They are usually identified shortly after birth. Peripheral Odontogenic Fibromas in Dogs This type of epulis (once known as a fibromatous epulis or an ossifying epulis) is the most common non-cancerous tumor found in dogs. Thus far, all the tested treatment procedures improved the signs of the disease but did not lengthen an affected dogs life. The disease may be inherited in Cocker Spaniels. They are found in older dogs and cats and appear closer to the surface of the skin. The skin bumps may come and go and do not typically cause itching. Surgical removal may be combined with radiation treatment or chemotherapy. Subungual squamous cell carcinomas are tumors that originate under a nail (claw). Fibromas are benign tumors that are composed of fibrous or connective tissue. Squamous cell carcinomas are malignant tumors which can look similar to gingival hyperplasia. When they happen on your gums, it's usually due to irritation from dentures or other oral devices. Career guidance - "It's easier to transition from tech to tech in training". Treatment is by surgical removal. A fine needle aspiration is necessary in order to exclude other types of tumors that can mimic lipomas, such as mast cell tumors (see below). For a small solitary tumor confined to the skin (Stage I), the preferred treatment is complete surgical removal. Regrowth is common within 1 year. They've said they want to train me to work in MRI. Treatment depends on the clinical stage of the disease and the predicted spread of an individual tumor. These tumors do not spread to other organs; however, extension to surrounding tissues is common. Histiocytomas are common skin tumors typically seen in younger dogs (less than 3 years old). They are more commonly called by other names such as reactive hyperplasia, traumatic fibroma, focal intraoral fibrous hyperplasia, oral polyp, or a fibrous nodule. Lipomas typically appear as soft, occasionally thin, discrete lumpy masses; most move freely when touched. Apocrine gland adenocarcinomas are malignant tumors of sweat glands. Biopsy evaluation (laboratory study of a tissue sample taken from the tumor) is the best means of diagnosis. The stroma is loose and has low cellularity of mesenchymal cells, unlike a neurofibroma. Chronic irritation and trauma can result in the formation of fibrous tissue masses called fibromas. Surgical removal of both forms is generally effective. Fibromas occur in all domestic species but are primarily a tumor of senior dogs. Siberian Huskies, Irish Setters, German Shepherds, and mixed-breed dogs are most at risk. In general, when treatment fails it is due to late diagnosis and lack of control of the original tumor rather than spread of new tumors. Norwegian Elkhounds and Lhasa Apsos are at risk for developing widespread tumors. Swelling of the bones; . Two surgeons, a man and a woman, perform surgery to remove prostate adenoma and varicocele, fibroadenoma, operating theater Early treatment is critical for a positive outcome for a dog with a malignant melanoma. Two main types of epulides exist: peripheral odontogenic fibroma and acanthomatous ameloblastoma. They spread within the skin and may spread to regional lymph nodes late in the disease. Kerry Blue and Wheaten Terriers, Bouvier des Flandres, Bichons Frises, and Standard Poodles are most at risk. Benign melanomas (also called melanocytomas) are diagnosed much more frequently in dogs than malignant melanomas. Among dogs, Great Pyrenees, Chow Chows, and Alaskan Malamutes are the most commonly affected breeds. Canine extramedullary plasmacytomas are relatively common skin tumors in dogs. In dogs, these tumors are most commonly recognized in Peekapoos, Old English Sheepdogs, and English Springer Spaniels. They also get some solar radiation that reflects from the ground. Chemotherapy and other drugs may be used to treat systemic histiocytosis. They may, however, continue to grow to the point of becoming irritating or bothersome, but generally are slow growing. Fibromas . The ones found in dogs include infundibular follicular cysts, isthmus catagen cysts, matrix cysts, hybrid cysts (panfollicular cysts), and dermoid cysts. The vet checks these lumps underneath your dog's skin. They occur mostly on the skin of the face. If malignancy is suspected, tissue surrounding the tumor will also be removed to increase the chance that none of the tumor cells are left behind. They can mimic lipomas; therefore, visual signs alone cannot establish a diagnosis. In domestic animals, all hair follicles have apocrine glands, as do anal glands and ceruminous glands in the ears. Limiting exposure to excessive sunlight may help prevent squamous cell carcinomas. The presence of tumors with simultaneous leukemia is known as Szary syndrome. The overall complication rate following segmental mandibulectomy in dogs is 33%. Tumors may be benign or malignant (cancerous). Chemotherapy and radiation treatment may also be provided. Options include surgical removal of the mass and affected regional lymph nodes (if feasible), radiation, and chemotherapy. Although chemotherapy may improve the quality and prolong the life of an affected dog, it is seldom a complete cure. They most commonly happen after tail docking in dogs. These are discussed in the section on ear diseases Tumors of the Ear Canal in Dogs Tumors may develop from any of the structures lining or supporting the ear canal, including the outer layer of skin, the glands that produce earwax and oil, or any of the bones, connective tissues read more . They are common in dogs, with most located on the trunk and legs. Many breeds appear to be prone to the disease, especially Boxers and Pugs (in which tumors are often multiple), Rhodesian Ridgebacks, and Boston Terriers. Some tumors grow slowly, whereas others are more likely to spread or return within 20 weeks of surgical removal. Peripheral odontogenic fibroma This type of tumor may also be referred to as an ossifying epulis or a fibromatous epulis. Among dogs, Miniature and Standard Schnauzers and Scottish Terriers are most at risk. Fibromas are sometimes biopsied because they can be hard to distinguish from malignant gingival tumors. Although the appearance is variable, the tumors that spread to the skin are usually multiple, ulcerated lumps. One study provided a clinical and histopathological characterization of canine nasal angiofibroma in 13 dogs, but there . It is rare that fibrosarcomas metastasize (spread) to other parts of the body. Request an Appointment at Mayo Clinic Diagnosis Imaging tests may include: X-rays Ultrasound The nodules of nodular dermatofibrosis may continue to appear over time, making it seem as if it is spreading, but each nodule is independent of the other. Masses called fibromas m currently an RT student in my senior year a. 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